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KMID : 1123920020160010165
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Korean Journal of Oriental Physiology and Pathology
2002 Volume.16 No. 1 p.165 ~ p.171
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Study on the Function of Hyunsamchungpye-eum on Anti-inflammatory and Anti-allergic Action
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Seo Jung-Min
Kim Jin-Su
Lee Kwang-Gyu
Yuk Sang-Won
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Abstract
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The purpose of this research was to investigate effects of Hyunsamchungpye-eum(HSCPE) on the anti-inflammatory/anti-allergic reaction in vivo and in vitro. HSCPE reduced the acute hind paw edema induced by histamine, the permeability of evans blue into peritoneal cavity. HSCPE inhibited the passive cutaneous anaphylaxis reaction in rat, the lethal anaphylaxis and degranulation of peritoneal mast cells induced by compound 48/80 in mice, HSCPE did not affect the Arthus reaction, but decreased the delayed type hypersensitivity induced by SRBC, contact dermititis induced by DNFB. These results suggest that HSCPE have an anti-inflammatory and anti-allergic action.
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KEYWORD
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Hyunsamchungpye-eum(玄蔘淸肺飮), anti-inflammatory/anti-allergic reaction
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